The CTRC is a pan-Canadian collaborative research network created to enhance research capacity amongst Canadian scientists working on different aspects of the continuum of care for traumatic brain injury (TBI) patients, including prevention, acute care, up to rehabilitation and long-term care. The network, established in 2015 with support of the CIHR, is formed of over 150researchers and 300 trainees or research coordinators/associates from over 70institutions across Canada. Over the years, several investigator-led large-scale multicenter pan-Canadian and international trials have been developed within the network. The CTRC is a model of collaborative research group within the TBI research community globally.