Currently, researchers who wish to conduct a multicentre randomized controlled trial (RCT) in Canada are required to get multiple research ethics boards (REB) approvals across the different research centres. This leads to lengthy delays in the approval process, and can delay the start times of RCTs in Canada.

Other countries worldwide (e.g., Australia, Brazil, Denmark, Spain, United Kingdom, United States) have adopted a single national REB approval process to improve the efficiency of conducting multicentre RCTs and avoid unnecessary duplication of work.

As part of ACT Canada’s mandate to improve the ecosystem for conducting clinical trials in Canada, we are holding an open competition to select a group to set up and run a sustainable pan-Canadian, distributive, single research ethics board (REB) review and approval process with strict timelines, for the initiation and conduct of multicentre randomized controlled trials (RCTs) in Canada.

Applicants can request up to $250,000 (CAN) in funding to help set up, initiate, and conduct the pan-Canadian, distributive, single REB review and approval process with strict timelines.


For an application to be eligible, it must fulfill the following criteria.

  1. The group’s leadership positions must include an individual from at least 6 of Canada’s provinces and territories.
  2. The group submitting the application must have prior experience serving on or running an REB in Canada.
  3. The group submitting the application must also be affiliated with an organization eligible to hold CIHR funding.

The deadline to apply is Friday August 16th, 2024 at noon ET

Application Process:

For full instructions on the application process, please see the Call for Proposals PDF. 

The application portal can be found here:

If you have questions about the application process, please reach out to us at: