Dr. Salim Yusuf is Executive Director of the ACT Coordinating Centre, PHRI, and a principal applicant of the ACT consortium. He has led >50 major RCTs in >100 countries and several of these have changed medical practice worldwide. He has published >1200 articles in refereed journals, he was the second most cited researcher in the world in 2011, and the highest cited researcher in cardiology for several years. He is the highest cited scientist in the world for clinical trials, 8th in all fields of medicine combined, 2nd in Canada, and has the 17th highest h-index (267) globally. He has set standards for large simple trials, and has established a network for clinical trials at >1000 centres in >60 countries. He has received >70 awards including the Order of Canada, Gairdner-Wightman Award, Killam Prize, Canadian Medical Hall of Fame, Gold Medal of the Royal Society of Canada, and awards from many major international cardiology societies including the World Heart Federation’s Lifetime Research Achievement Award. He has served on advisory committees for the US FDA, and has obtained regulatory approvals based on his research for new drugs in Canada, the US, the UK, and Europe.