CANet is a leading cardiovascular multidisciplinary and multi-sectoral pan-Canadian network focused on patient-driven discovery and innovation. The network has over 250 investigators across 31 university/research institutions and has funded 70 research projects producing 1472 peer-reviewed publications resulting in numerous practice and guideline changes. CANet has helped to train over 550 trainees and launch 147 new careers in public and private sectors. CANet is supported by a $43M investment by the Federal Government matched with $55M across CANet’s 200 partners from industry, government, and academic institutes.